I Am Not a Tractor! How Florida Farmworkers Took on the Fast Food Giants and Won

[Excerpt from jacket] I Am Not a Tractor! celebrates the courage, vision, and creativity of the farmworkers and community leaders who have transformed one of the worst agricultural situations in the United States into one of the best. Susan L. Marquis highlights past abuses workers in Florida\u27s tomato fields: toxic pesticide exposure, beatings, sexual assault, rampant wage theft, and even, astonishingly, modern-day slavery. Marquis unveils how, even without new legislation, regulation, or government participation, these farmworkers have dramatically improved their work conditions. Marquis credits this success to the immigrants from Mexico, Haiti, and Guatemala who formed the Coalition of Immokalee Workers, a neuroscience major who takes great pride in the watermelon crew he runs, a leading farmer/grower who was once homeless, and a retired New York State judge who volunteered to stuff envelopes and ended up building a groundbreaking institution. Through the Fair Food Program that they have developed, fought for, and implemented, these people have changed the lives of more than thirty thousand field workers. I Am Not a Tractor! offers a range of solutions to a problem that is rooted in our nation\u27s slave history and that is worsened by ongoing conflict over immigration

Examining different forms of implementation and in early childhood curriculum research

The purpose of this study was to examine different approaches to assessing implementation in an early childhood curriculum research study. Early childhood teachers in 51 preschool classes located at nationally dispersed sites implemented the Children's School Success curriculum for a school year. Structural (proportion of curriculum delivered) and process (quality of delivery of curriculum) measures of implementation were collected for the literacy, math, and social components of the curriculum. Also, a multiplicative composite score incorporating information from the structural and process measures was calculated. Site differences occurred for the process measure, but not the structural and composite measures. Analysis of the process implementation measures collected across time revealed primarily stable trends across sites. Significant associations were found between measures of implementation and some of the child outcome variables, with the different forms of implementatio

Collision, Collusion and Coincidence: Pop Art’s Fairground Parallel

This article looks at parallel methods, motivations and modes of consumption between formative British pop art and British fairground art. I focus on two strands, the emergent critical work of the Independent Group and the school of artists based at the Royal College of Art under the nominal leadership of Peter Blake. I use iconographical and iconological methods to compare the content of the art, and then examine how pop art tried to create both a critical and playful distancing from established rules and practices of the artistic canon. I focus on non-institutional cultural groupings and diffuse production and consumption models

Toward visualization of nanomachines in their native cellular environment

The cellular nanocosm is made up of numerous types of macromolecular complexes or biological nanomachines. These form functional modules that are organized into complex subcellular networks. Information on the ultra-structure of these nanomachines has mainly been obtained by analyzing isolated structures, using imaging techniques such as X-ray crystallography, NMR, or single particle electron microscopy (EM). Yet there is a strong need to image biological complexes in a native state and within a cellular environment, in order to gain a better understanding of their functions. Emerging methods in EM are now making this goal reachable. Cryo-electron tomography bypasses the need for conventional fixatives, dehydration and stains, so that a close-to-native environment is retained. As this technique is approaching macromolecular resolution, it is possible to create maps of individual macromolecular complexes. X-ray and NMR data can be ‘docked’ or fitted into the lower resolution particle density maps to create a macromolecular atlas of the cell under normal and pathological conditions. The majority of cells, however, are too thick to be imaged in an intact state and therefore methods such as ‘high pressure freezing’ with ‘freeze-substitution followed by room temperature plastic sectioning’ or ‘cryo-sectioning of unperturbed vitreous fully hydrated samples’ have been introduced for electron tomography. Here, we review methodological considerations for visualizing nanomachines in a close-to-physiological, cellular context. EM is in a renaissance, and further innovations and training in this field should be fully supported

Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders

Genetic influences on psychiatric disorders transcend diagnostic boundaries, suggesting substantial pleiotropy of contributing loci. However, the nature and mechanisms of these pleiotropic effects remain unclear. We performed analyses of 232,964 cases and 494,162 controls from genome-wide studies of anorexia nervosa, attention-deficit/hyper-activity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, and Tourette syndrome. Genetic correlation analyses revealed a meaningful structure within the eight disorders, identifying three groups of inter-related disorders. Meta-analysis across these eight disorders detected 109 loci associated with at least two psychiatric disorders, including 23 loci with pleiotropic effects on four or more disorders and 11 loci with antagonistic effects on multiple disorders. The pleiotropic loci are located within genes that show heightened expression in the brain throughout the lifespan, beginning prenatally in the second trimester, and play prominent roles in neurodevelopmental processes. These findings have important implications for psychiatric nosology, drug development, and risk prediction.Peer reviewe

Finishing the euchromatic sequence of the human genome

The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead

Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors

Background Suicide is a leading cause of death worldwide, and nonfatal suicide attempts, which occur far more frequently, are a major source of disability and social and economic burden. Both have substantial genetic etiology, which is partially shared and partially distinct from that of related psychiatric disorders. Methods We conducted a genome-wide association study (GWAS) of 29,782 suicide attempt (SA) cases and 519,961 controls in the International Suicide Genetics Consortium (ISGC). The GWAS of SA was conditioned on psychiatric disorders using GWAS summary statistics via multitrait-based conditional and joint analysis, to remove genetic effects on SA mediated by psychiatric disorders. We investigated the shared and divergent genetic architectures of SA, psychiatric disorders, and other known risk factors. Results Two loci reached genome-wide significance for SA: the major histocompatibility complex and an intergenic locus on chromosome 7, the latter of which remained associated with SA after conditioning on psychiatric disorders and replicated in an independent cohort from the Million Veteran Program. This locus has been implicated in risk-taking behavior, smoking, and insomnia. SA showed strong genetic correlation with psychiatric disorders, particularly major depression, and also with smoking, pain, risk-taking behavior, sleep disturbances, lower educational attainment, reproductive traits, lower socioeconomic status, and poorer general health. After conditioning on psychiatric disorders, the genetic correlations between SA and psychiatric disorders decreased, whereas those with nonpsychiatric traits remained largely unchanged. Conclusions Our results identify a risk locus that contributes more strongly to SA than other phenotypes and suggest a shared underlying biology between SA and known risk factors that is not mediated by psychiatric disorders.Peer reviewe

I Am Not a Tractor! How Florida Farmworkers Took on the Fast Food Giants and Won

The abstract, table of contents, and first twenty-five pages are published with permission from the Cornell University Press. For ordering information, please visit the Cornell University Press at http://www.cornellpress.cornell.edu/.[Excerpt from jacket] I Am Not a Tractor! celebrates the courage, vision, and creativity of the farmworkers and community leaders who have transformed one of the worst agricultural situations in the United States into one of the best. Susan L. Marquis highlights past abuses workers in Florida's tomato fields: toxic pesticide exposure, beatings, sexual assault, rampant wage theft, and even, astonishingly, modern-day slavery. Marquis unveils how, even without new legislation, regulation, or government participation, these farmworkers have dramatically improved their work conditions. Marquis credits this success to the immigrants from Mexico, Haiti, and Guatemala who formed the Coalition of Immokalee Workers, a neuroscience major who takes great pride in the watermelon crew he runs, a leading farmer/grower who was once homeless, and a retired New York State judge who volunteered to stuff envelopes and ended up building a groundbreaking institution. Through the Fair Food Program that they have developed, fought for, and implemented, these people have changed the lives of more than thirty thousand field workers. I Am Not a Tractor! offers a range of solutions to a problem that is rooted in our nation's slave history and that is worsened by ongoing conflict over immigration.Marquis__I_Am_Not_a_Tractor_How_FL_Farmworkers_Took_on_the_Fast_Food_Giants_and_Won.pdf: 319 downloads, before Oct. 1, 2020